5 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/17/1942 | H | Rio Grande | W | 25 | 0 | 1-0 | 1,000 | Louisville | Ky. | Maxwell Field | |||||
| 09/26/1942 | A | Cincinnati | L | 0 | 51 | 1-1 | Cincinnati | Ohio | Nippert Stadium | ||||||
| 10/10/1942 | A | Evansville | W | 20 | 0 | 2-1 | Evansville | Ind. | Enlow Field | ||||||
| 10/17/1942 | H | DePauw | L | 6 | 19 | 2-2 | Louisville | Ky. | Maxwell Field | ||||||
| 10/24/1942 | H | Indiana State | L | 7 | 25 | 2-3 | Louisville | Ky. | Maxwell Field |