11 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/13/1975 | H | Western Kentucky | L | 17 | 21 | 0-1 | 34,077 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 09/20/1975 | A | Drake | L | 7 | 31 | 0-2 | 8,120 | Des Moines | Iowa | ||||||
| 09/27/1975 | H | Cincinnati | L | 27 | 46 | 0-3 | 13,867 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/04/1975 | A | Wichita State | L | 10 | 13 | 0-4 | 12,765 | Wichita | Kan. | ||||||
| 10/11/1975 | H | Chattanooga | W | 6 | 3 | 1-4 | 9,056 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/18/1975 | A | Memphis | L | 7 | 41 | 1-5 | 15,480 | Memphis | Tenn. | Liberty Bowl Memorial Stadium | |||||
| 10/25/1975 | H | Mississippi State | W | 14 | 28 | 2-5 | 8,636 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 11/01/1975 | A | Tulsa | L | 14 | 38 | 2-6 | 14,500 | Tulsa | Okla. | ||||||
| 11/08/1975 | H | Dayton | L | 13 | 32 | 2-7 | 9,888 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 11/15/1975 | A | Louisiana-Monroe | L | 10 | 14 | 2-8 | 6,700 | Monroe | La. | ||||||
| 11/22/1975 | A | West Texas State | L | 23 | 49 | 2-9 | 6,200 | Canyon | Texas |